I just spent a miserable three months hammering weekly at the Lavasoft "help" site trying to get rid of the About:Blank hijack. I'm on a Win2K box running SP4, IE6 SP1.
Everything they suggested (repeatedly, whether it worked at all or not) did nothing. Or at least nothing permenant.
This is what I did to get rid of it, and it seems to work like a champ:
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Run AdAware current version and delete all the crap it finds.
Run About:Buster's latest version.
After running the A:B, I rebooted. The boot into Win2K was interreupted by a messagebox asking me if I wanted to run a .dat. I said no ("cancel") - the machine finished booting and the IE home page was still "About:Blank", but actually blank.
I went to my system32 directory (C:\WINNT\system32), and sorted by file type. I found about 20 .dat files with seemingly random file names, all 6 chars long. I then sorted by file size, and deleted (actually, I just moved them to a new directory first, then deleted after another successful reboot) every .dat that was 91k in size.
Everything is back to normal now, after resetting my home page to the one I wanted.
Seems a lot simpler than running HJT! and AB a zillion times, don't it?
Hope this helps, gang...
c.